Molecular Combing of DNA: Methods and Applications

First proposed in 1994, molecular combing of DNA is a technique that allowsadsorption and alignment on the surface with no need for prior modi-fication molecule. Since then, many variations original methodhave been devised used wide range applications from genomicstudies to nanoelectronics. While has applied avariety DNA-related studies, comprehensive review publishedon different methods so far. In this review, underly-ing mechanisms are described followed bydiscussion main as well its majorapplications nanotechnology.